Using phosphatidylserine exposure on apoptotic cells to stimulate myoblast fusion.
Methods Mol Biol
; 1313: 141-8, 2015.
Article
em En
| MEDLINE
| ID: mdl-25947662
ABSTRACT
The fusion of myoblasts, the skeletal muscle progenitors, is critical for skeletal muscle formation, function, and repair after muscle injury. Recognition of the phospholipid phosphatidylserine (PtdSer) exposed on certain myoblasts is required during fusion into multinuclear myofibers. Cell surface exposure of PtdSer is also a feature of cells dying through the process of apoptosis. Here, we describe the use of PtdSer exposing apoptotic cells as stimulators of myoblast fusion.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fosfatidilserinas
/
Fusão Celular
/
Desenvolvimento Muscular
/
Mioblastos
Limite:
Animals
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article