A study on gastric ulcers induced by long-term fasting in rats.
Scand J Gastroenterol Suppl
; 162: 75-8, 1989.
Article
em En
| MEDLINE
| ID: mdl-2595313
ABSTRACT
The present study was performed to investigate the roles of intragastric pH and PAS positive mucus as to the incidence of gastric ulcers after long-term fasting in rats. Gastric ulcers in the forestomach and corpus were found at 4 and 6 days after fasting, respectively. The intragastric pH was significantly reduced at 1, 2, 3, 4, 6 and 7 days after fasting, but tended to have returned to control levels at 8 days. PAS positive mucus was significantly increased at 2 to 7 days, but there was no significant change at 8 days. From these results, it seems that the aggressive factor is not involved, but attenuation of the defensive factor is important as to the incidence of this type of ulcer. As one of the causes of this attenuation, a decrease in the gastric mucus volume was suggested.
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Base de dados:
MEDLINE
Assunto principal:
Úlcera Gástrica
/
Jejum
Limite:
Animals
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article