Embolization of renal arteries before transplantation in patients with polycystic kidney disease: a single institution long-term experience.
Eur Radiol
; 25(11): 3263-71, 2015 Nov.
Article
em En
| MEDLINE
| ID: mdl-25981217
ABSTRACT
PURPOSE:
We aimed to retrospectively assess the long-term safety and efficacy of embolization of renal arteries (ERA) in patients with polycystic kidney disease (PKD) before renal transplantation. MATERIAL ANDMETHODS:
Between January 2008 and November 2013, 82 ERA procedures were performed on 76 kidneys in 73 patients (mean age 53 years, range 34-72). All patients had terminal-stage PKD and were under dialysis and on the renal transplant waiting list with a temporary contraindication due to excessive renal volume.RESULTS:
ERA was considered successful in 89.5% (68/76) of embolized kidneys, meaning that the temporary contraindication for transplantation could be withdrawn for 65 patients (on average 5.6 months, range 2.8-24.3, after ERA). Mean volume reduction was 40 (range 2-69) at 3 months and 59% (35-86) thereafter (both p < 0.001). Post-embolization syndrome occurred after 15 of 82 procedures (18.3%). The severe complication rate was 4.9%. Forty-three (67.7%) transplantations were successfully conducted after ERA, with a mean follow-up of 26.2 months (range 1.8-59.5), and the estimated 5-year graft survival rate was 95.3% [95% CI 82.7-98.8].CONCLUSIONS:
ERA is a safe and effective alternative to nephrectomy before renal transplantation in patients with PKD. KEY POINTS ⢠Embolization of non-functioning polycystic kidneys allowed transplantation in 89.5% of cases. ⢠Technical failure rate was 7.9% after embolization, irrespective of the technique used. ⢠Post-embolization syndrome occurred after 18.3% of the procedures. ⢠A low rate of severe complications (4.9%) was observed after renal embolization.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Artéria Renal
/
Transplante de Rim
/
Embolização Terapêutica
/
Doenças Renais Policísticas
Tipo de estudo:
Observational_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article