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A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
Lasagna-Reeves, Cristian A; Rousseaux, Maxime Wc; Guerrero-Muñoz, Marcos J; Park, Jeehye; Jafar-Nejad, Paymaan; Richman, Ronald; Lu, Nan; Sengupta, Urmi; Litvinchuk, Alexandra; Orr, Harry T; Kayed, Rakez; Zoghbi, Huda Y.
Afiliação
  • Lasagna-Reeves CA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
  • Rousseaux MW; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
  • Guerrero-Muñoz MJ; Department of Neurology, University of Texas Medical Branch, Galveston, United States.
  • Park J; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
  • Jafar-Nejad P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
  • Richman R; Department of Molecular and Human Genetics, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, United States.
  • Lu N; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
  • Sengupta U; Department of Neurology, University of Texas Medical Branch, Galveston, United States.
  • Litvinchuk A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
  • Orr HT; Institute for Translational Neuroscience, University of Minnesota, Minnesota, United States.
  • Kayed R; Department of Neurology, University of Texas Medical Branch, Galveston, United States.
  • Zoghbi HY; Department of Molecular and Human Genetics, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, United States.
Elife ; 42015 May 19.
Article em En | MEDLINE | ID: mdl-25988806
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cerebelo / Ataxias Espinocerebelares / Ataxina-1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cerebelo / Ataxias Espinocerebelares / Ataxina-1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article