Efficacy of ivermectin in the treatment of induced Parascaris equorum infection in pony foals.
J Am Vet Med Assoc
; 195(12): 1712-4, 1989 Dec 15.
Article
em En
| MEDLINE
| ID: mdl-2599956
ABSTRACT
Eighteen pony foals inoculated with 1,500 +/- 109 infective Parascaris equorum eggs were given 0.02 ml of ivermectin vehicle (liquid)/kg of body weight, PO, (control); 0.2 mg of ivermectin paste/kg, PO; or 0.2 mg ivermectin liquid/kg, PO, on postinoculation day (PID) 28. Foals were euthanatized on PID 42, and the small intestinal contents were examined for P equorum larvae. The mean number of fourth-stage P equorum larvae in foals treated with ivermectin paste and liquid were 3.5 and 6, respectively. Significantly (P less than 0.01) higher mean numbers of larvae (1,250) were detected in foals treated with ivermectin vehicle. Larvae recovered from foals treated with ivermectin vehicle were of significantly (P less than 0.002) longer mean length than those from foals treated with ivermectin paste or liquid. Gross examination of lungs and liver revealed similar pathologic changes from the migration of P equorum in all foals. Adverse reaction to treatment was not observed.
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Base de dados:
MEDLINE
Assunto principal:
Ivermectina
/
Doenças dos Cavalos
/
Enteropatias Parasitárias
/
Infecções por Nematoides
Limite:
Animals
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article