Inflammation fuels tumor progress and metastasis.
Curr Pharm Des
; 21(21): 3032-40, 2015.
Article
em En
| MEDLINE
| ID: mdl-26004407
ABSTRACT
Inflammation is a beneficial response that can remove pathogens, repair injured tissue and restore homeostasis to damaged tissues and organs. However, increasing evidence indicate that chronic inflammation plays a pivotal role in tumor development, as well as progression, metastasis, and resistance to chemotherapy. We will review the current knowledge regarding the contribution of inflammation to epithelial mesenchymal transition. We will also provide some perspectives on the relationship between ER-stress signals and metabolism, and the role of these processes in the development of inflammation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Inflamação
/
Metástase Neoplásica
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Neoplasias
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article