Patient-Specific Induced Pluripotent Stem Cell-Derived RPE Cells: Understanding the Pathogenesis of Retinopathy in Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency.

Polinati, Padmini P; Ilmarinen, Tanja; Trokovic, Ras; Hyotylainen, Tuulia; Otonkoski, Timo; Suomalainen, Anu; Skottman, Heli; Tyni, Tiina

Polinati, Padmini P; Ilmarinen, Tanja; Trokovic, Ras; Hyotylainen, Tuulia; Otonkoski, Timo; Suomalainen, Anu; Skottman, Heli; Tyni, Tiina.

Afiliação

Polinati PP; Research Program of Molecular Neurology, Biomedicum 1, University of Helsinki, Helsinki, Finland.
Ilmarinen T; Institute of Biomedical Technology, University of Tampere, Tampere, Finland 3BioMediTech, Tampere, Finland.
Trokovic R; Research Program of Molecular Neurology, Biomedicum 1, University of Helsinki, Helsinki, Finland.
Hyotylainen T; Valtion Teknillinen Tutkimuskeskus (VTT) Technical Research Centre of Finland, Tietotie 2, Espoo, Finland.
Otonkoski T; Research Program of Molecular Neurology, Biomedicum 1, University of Helsinki, Helsinki, Finland 5Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland.
Suomalainen A; Research Program of Molecular Neurology, Biomedicum 1, University of Helsinki, Helsinki, Finland 5Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland.
Skottman H; Institute of Biomedical Technology, University of Tampere, Tampere, Finland 3BioMediTech, Tampere, Finland.
Tyni T; Research Program of Molecular Neurology, Biomedicum 1, University of Helsinki, Helsinki, Finland 5Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland.

Invest Ophthalmol Vis Sci ; 56(5): 3371-82, 2015 May.

Article em En | MEDLINE | ID: mdl-26024122

Assuntos

Células-Tronco Pluripotentes Induzidas/citologia; 3-Hidroxiacil-CoA Desidrogenase de Cadeia Longa/deficiência; Doenças Retinianas/patologia; Epitélio Pigmentado da Retina/patologia; Biomarcadores/metabolismo; Linhagem Celular; Células Cultivadas; Células Epiteliais/metabolismo; Células Epiteliais/ultraestrutura; Humanos; Imuno-Histoquímica; Lipídeos/análise; Espectrometria de Massas; Mitocôndrias/enzimologia; Doenças Retinianas/metabolismo; Epitélio Pigmentado da Retina/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Retinianas / Epitélio Pigmentado da Retina / Células-Tronco Pluripotentes Induzidas / 3-Hidroxiacil-CoA Desidrogenase de Cadeia Longa Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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