JMJD5 interacts with p53 and negatively regulates p53 function in control of cell cycle and proliferation.

Huang, Xiaobin; Zhang, Shuilian; Qi, Hongyan; Wang, Zhengyang; Chen, Hong-Wu; Shao, Jimin; Shen, Jing

Huang, Xiaobin; Zhang, Shuilian; Qi, Hongyan; Wang, Zhengyang; Chen, Hong-Wu; Shao, Jimin; Shen, Jing.

Afiliação

Huang X; Department of Pathology and Pathophysiology, Research Center for Air Pollution and Health, Zhejiang University School of Medicine, Hangzhou 310058, China.
Zhang S; Department of Pathology and Pathophysiology, Research Center for Air Pollution and Health, Zhejiang University School of Medicine, Hangzhou 310058, China.
Qi H; Department of Pathology and Pathophysiology, Research Center for Air Pollution and Health, Zhejiang University School of Medicine, Hangzhou 310058, China.
Wang Z; Department of Pulmonology, Sir Run Run Shaw Hospital, Hangzhou 310016, China.
Chen HW; Department of Biochemistry and Molecular Medicine, University of California at Davis, Sacramento, CA, USA.
Shao J; Department of Pathology and Pathophysiology, Research Center for Air Pollution and Health, Zhejiang University School of Medicine, Hangzhou 310058, China. Electronic address: shaojimin@zju.edu.cn.
Shen J; Department of Pathology and Pathophysiology, Research Center for Air Pollution and Health, Zhejiang University School of Medicine, Hangzhou 310058, China. Electronic address: shenjingwzy@zju.edu.cn.

Biochim Biophys Acta ; 1853(10 Pt A): 2286-95, 2015 Oct.

Article em En | MEDLINE | ID: mdl-26025680

Assuntos

Ciclo Celular; Histona Desmetilases/metabolismo; Neoplasias/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Linhagem Celular Tumoral; Inibidor de Quinase Dependente de Ciclina p21/genética; Inibidor de Quinase Dependente de Ciclina p21/metabolismo; Dano ao DNA; Histona Desmetilases/genética; Humanos; Neoplasias/tratamento farmacológico; Neoplasias/genética; Neoplasias/patologia; Estrutura Terciária de Proteína; Ribonucleotídeo Redutases/genética; Ribonucleotídeo Redutases/metabolismo; Proteína Supressora de Tumor p53/genética

Palavras-chave

Cancer development; Cell cycle; Gene transcription; JMJD5; p53 tumor suppressor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciclo Celular / Proteína Supressora de Tumor p53 / Histona Desmetilases / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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