Unusual serological response to hepatitis E virus in plasma donors consistent with re-infection.
Vox Sang
; 109(4): 406-9, 2015 Nov.
Article
em En
| MEDLINE
| ID: mdl-26031310
ABSTRACT
Hepatitis E virus (HEV)-positive plasma donations, identified by a plasma mini-pool screening approach, were analysed using serological methods for the presence of anti-HEV IgM and IgG. Avidity testing was performed on the IgG-reactive donations. Anti-HEV IgG with high avidity was observed in two donors together with high viral loads, but with the absence of anti-HEV IgM. These data are suggestive of re-infection in a small proportion of plasma donors, which has not previously been reported.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doadores de Sangue
/
Vírus da Hepatite E
/
Hepatite E
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article