A Polymeric Bowl for Multi-Agent Delivery.
Macromol Rapid Commun
; 36(16): 1498-504, 2015 Aug.
Article
em En
| MEDLINE
| ID: mdl-26033149
ABSTRACT
This paper describes a simple system for multi-agent delivery. The system consists of a biodegradable polymer particle with a hollow interior, together with a hole on its surface that can be completely or partially sealed via thermal annealing. A hydrophobic dye, Nile-red, entrapped within the shell of hollow particles presents a sustained release behavior while methylene blue, a hydrophilic model agent, encapsulated in the hollow interior shows a fast release manner. The release profiles of the probes can be further independently controlled by encapsulating methylene blue-loaded polymer nanoparticles, instead of free dye, in the hollow particle with a small hole on its surface.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Nanopartículas
/
Plásticos Biodegradáveis
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article