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Delusional disorder and schizophrenia: a comparison of the neurocognitive and clinical characteristics in first-episode patients.
Hui, C L M; Lee, E H M; Chang, W C; Chan, S K W; Lin, J; Xu, J Q; Chen, E Y H.
Afiliação
  • Hui CL; Department of Psychiatry,University of Hong Kong,Hong Kong SAR,China.
  • Lee EH; Department of Psychiatry,University of Hong Kong,Hong Kong SAR,China.
  • Chang WC; Department of Psychiatry,University of Hong Kong,Hong Kong SAR,China.
  • Chan SK; Department of Psychiatry,University of Hong Kong,Hong Kong SAR,China.
  • Lin J; Department of Psychiatry,University of Hong Kong,Hong Kong SAR,China.
  • Xu JQ; Department of Psychiatry,University of Hong Kong,Hong Kong SAR,China.
  • Chen EY; Department of Psychiatry,University of Hong Kong,Hong Kong SAR,China.
Psychol Med ; 45(14): 3085-95, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26036591
ABSTRACT

BACKGROUND:

Delusional disorder (DD) is thought to be distinct from schizophrenia (SZ). However, few systematic investigations have been conducted on DD because of the difficulty in ascertaining a representative sample size. Existing knowledge has been mostly generated from inpatient cohorts, which may be biased towards a more severe sample.

METHOD:

We compared the demographic, clinical and cognitive differences between 71 patients with first-episode DD and 71 age-matched patients with first-episode SZ. Participants were consecutively recruited from a population-based territory-wide study of early psychosis in Hong Kong targeting first-episode psychosis. Basic demographic information, premorbid functioning, duration of untreated psychosis, pathways to care, symptomatology, social, occupational, and cognitive functioning were comprehensively assessed using standardized measurements.

RESULTS:

Patients with DD had less premorbid schizoid and schizotypal traits compared to patients with SZ. More patients with DD were married compared to patients with SZ. However, at first episode, there were no significant differences between the two groups in regards to the duration of untreated psychosis, pathways to care, symptom severity, neurocognitive performance, treatment, and functioning.

CONCLUSIONS:

Our findings challenge previous thinking that patients with DD had better functioning than patients with SZ. This study not only provides an updated perspective into conceptualizing the clinical differences between DD and SZ, but also expands the descriptive account of the two disorders to include the neurocognitive dimension.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Esquizofrenia Paranoide / Cognição / Delusões / Comportamento de Busca de Ajuda / Ciúme Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Esquizofrenia Paranoide / Cognição / Delusões / Comportamento de Busca de Ajuda / Ciúme Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article