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Metformin increases degradation of phospholamban via autophagy in cardiomyocytes.
Teng, Allen C T; Miyake, Tetsuaki; Yokoe, Shunichi; Zhang, Liyong; Rezende, Luís Mário; Sharma, Parveen; MacLennan, David H; Liu, Peter P; Gramolini, Anthony O.
Afiliação
  • Teng AC; Department of Physiology, University of Toronto, Toronto, ON, Canada M5G 1L7; Toronto General Hospital, University Health Network, Toronto, ON, Canada M5G 1L7;
  • Miyake T; Department of Physiology, University of Toronto, Toronto, ON, Canada M5G 1L7; Toronto General Hospital, University Health Network, Toronto, ON, Canada M5G 1L7;
  • Yokoe S; Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada M5G 1L6;
  • Zhang L; Toronto General Hospital, University Health Network, Toronto, ON, Canada M5G 1L7; University of Ottawa Heart Institute, Ottawa, ON, Canada K1Y 4W7;
  • Rezende LM; Department of Physiology, University of Toronto, Toronto, ON, Canada M5G 1L7; Toronto General Hospital, University Health Network, Toronto, ON, Canada M5G 1L7;
  • Sharma P; Department of Physiology, University of Toronto, Toronto, ON, Canada M5G 1L7;
  • MacLennan DH; Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada M5G 1L6; david.maclennan@utoronto.ca anthony.gramolini@utoronto.ca.
  • Liu PP; Toronto General Hospital, University Health Network, Toronto, ON, Canada M5G 1L7; University of Ottawa Heart Institute, Ottawa, ON, Canada K1Y 4W7;
  • Gramolini AO; Department of Physiology, University of Toronto, Toronto, ON, Canada M5G 1L7; Toronto General Hospital, University Health Network, Toronto, ON, Canada M5G 1L7; Ted Rogers Centre for Heart Research, Toronto, ON, Canada M5G 1L7 david.maclennan@utoronto.ca anthony.gramolini@utoronto.ca.
Proc Natl Acad Sci U S A ; 112(23): 7165-70, 2015 Jun 09.
Article em En | MEDLINE | ID: mdl-26040000
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Proteínas de Ligação ao Cálcio / Miócitos Cardíacos / Metformina Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Proteínas de Ligação ao Cálcio / Miócitos Cardíacos / Metformina Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article