Autofagia; Distonia/patologia; Células Receptoras Sensoriais/patologia; Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Animais; Proteínas de Transporte/genética; Proteínas do Citoesqueleto/genética; Complexo Dinactina; Distonia/metabolismo; Distonina; Proteínas de Choque Térmico/metabolismo; Camundongos Transgênicos; Proteínas Associadas aos Microtúbulos/metabolismo; Microtúbulos/metabolismo; Proteínas do Tecido Nervoso/genética; Fagossomos/metabolismo; Fagossomos/ultraestrutura; Células Receptoras Sensoriais/metabolismo; Células Receptoras Sensoriais/ultraestrutura; Proteína Sequestossoma-1

ANOVA, analysis of variance; BPAG1; CASP3, caspase 3, apoptosis-related cysteine peptidase; DMC; DMC, dynein/dynactin motor complex; DMEM, Dulbecco's modified Eagle's medium; DNAIC1, dynein, axonemal, intermediate chain 1; DRG, dorsal root ganglion; DST, dystonin; Dstdt, dystonia musculorum; EM, electron microscopy; FBS, fetal bovine serum; HSAN-VI; HSAN-VI, hereditary sensory and autonomic neuropathy type VI; MACF1, microtubule-actin crosslinking factor 1; MAP1B; MAP1B, microtubule-associated protein 1B; MAP1LC3/LC3, microtubule associated-protein 1 light chain 3; MT, microtubule; P, postnatal day; PBS, phosphate-buffered saline; PCR, polymerase chain reaction; PrP, prion protein; RT-PCR, reverse transcription-polymerase chain reaction; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; SQTSM1/p62, sequestosome 1; TCA, trichloroacetic acid; TUBB3, tubulin, ß, 3 class III; WT, wild type; autophagosome; dynein; dystonin; microtubules; trafficking