Topical Review: Translating Translational Research in Behavioral Science.

OBJECTIVE: To present a model of translational research for behavioral science that communicates the role of behavioral research at each phase of translation. METHODS: A task force identified gaps in knowledge regarding behavioral translational research processes and made recommendations regarding advancement of knowledge. RESULTS: A comprehensive model of translational behavioral research was developed. This model represents T1, T2, and T3 research activities, as well as Phase 1, 2, 3, and 4 clinical trials. Clinical illustrations of translational processes are also offered as support for the model. CONCLUSIONS: Behavioral science has struggled with defining a translational research model that effectively articulates each stage of translation and complements biomedical research. Our model defines key activities at each phase of translation from basic discovery to dissemination/implementation. This should be a starting point for communicating the role of behavioral science in translational research and a catalyst for better integration of biomedical and behavioral research.