Magnetic molecularly imprinted polymer for the efficient and selective preconcentration of diazinon before its determination by high-performance liquid chromatography.
J Sep Sci
; 38(16): 2797-803, 2015 Aug.
Article
em En
| MEDLINE
| ID: mdl-26082081
ABSTRACT
A molecularly imprinted polymer was selectively applied for solid-phase extraction and diazinon residues enrichment before high-performance liquid chromatography. Diazinon was thermally copolymerized with Fe3 O4 @polyethyleneglycol nanoparticles, methacrylic acid (functional monomer), 2-hydroxyethyl methacrylate (co-monomer), and ethylene glycol dimethacrylate (cross-linking monomer) in the presence of acetonitrile (porogen) and 2,2-azobisisobutyronitrile (initiator). Then, the imprinted diazinon was reproducibly eluted with methanol/acetic acid (91, v/v). The sorbent particles were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy. The comprehensive study of variables through experimental design showed that the maximum performance was achieved under these conditions pH 7, 10 mL sample volume, 15 mg sorbent, 10 min vortex time, 5 min ultrasonic time, 200 µL methanol/acetic acid (91, v/v) as eluent, and 5 min desorption time. Under optimized conditions, the molecularly imprinted polymer solid-phase extraction method demonstrated a linear range (0.02-5 g/mL), a correlation coefficient of 0.997, and 0.005 g/mL detection limit.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Diazinon
/
Extração em Fase Sólida
Tipo de estudo:
Evaluation_studies
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article