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The combination of methylsulfonylmethane and tamoxifen inhibits the Jak2/STAT5b pathway and synergistically inhibits tumor growth and metastasis in ER-positive breast cancer xenografts.
S P, Nipin; Darvin, Pramod; Yoo, Young Beom; Joung, Youn Hee; Kang, Dong Young; Kim, Don Nam; Hwang, Tae Sook; Kim, Sang Yoon; Kim, Wan Seop; Lee, Hak Kyo; Cho, Byung Wook; Kim, Heui Soo; Park, Kyung Do; Park, Jong Hwan; Chang, Soung Hoon; Yang, Young Mok.
Afiliação
  • S P N; Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul, 143-701, Korea. nipinsp@gmail.com.
  • Darvin P; Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul, 143-701, Korea. pramoddarvin@gmail.com.
  • Yoo YB; Department of Surgery, School of Medicine, Konkuk University, Seoul, 143-701, Korea. 0117652771@kuh.ac.kr.
  • Joung YH; Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul, 143-701, Korea. adada76@nate.com.
  • Kang DY; Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul, 143-701, Korea. kdy6459@naver.com.
  • Kim DN; Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul, 143-701, Korea. don1106@nate.com.
  • Hwang TS; Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul, 143-701, Korea. tshwang@kuh.ac.kr.
  • Kim SY; Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul, 143-701, Korea. sangyoon.kim@kku.ac.kr.
  • Kim WS; Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul, 143-701, Korea. wskim@kuh.ac.kr.
  • Lee HK; Genomic Informatics Center, Hankyong National University, Anseong, Korea. breedlee@empal.com.
  • Cho BW; Department of Animal Science, College of Life Sciences, Pusan National University, Pusan, Korea. bwcho@pusan.ac.kr.
  • Kim HS; Department of Biological Sciences, College of Natural Sciences, Pusan National University, Busan, Korea. khs307@pusan.ac.kr.
  • Park KD; Genomic Informatics Center, Hankyong National University, Anseong, Korea. doobalo@hknu.ac.kr.
  • Park JH; Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul, 143-701, Korea. nihpark@yahoo.com.
  • Chang SH; Department of Preventive Medicine, School of Medicine, Konkuk University, Chungju, 380-701, Korea. schang@kku.ac.kr.
  • Yang YM; Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul, 143-701, Korea. ymyang@kku.ac.kr.
BMC Cancer ; 15: 474, 2015 Jun 19.
Article em En | MEDLINE | ID: mdl-26084564

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonas / Tamoxifeno / Neoplasias da Mama / Dimetil Sulfóxido / Fator de Transcrição STAT5 / Janus Quinase 2 Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonas / Tamoxifeno / Neoplasias da Mama / Dimetil Sulfóxido / Fator de Transcrição STAT5 / Janus Quinase 2 Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article