[Role of bone-density-conserving agents in the treatment for pain in patients with bone metastases].
Vopr Onkol
; 61(2): 303-10, 2015.
Article
em Ru
| MEDLINE
| ID: mdl-26087615
ABSTRACT
Bones are the fourth area of metastases of malignant tumors that significantly burden the disease reducing the quality of life of a patient as cause pain, threat pathological fracture, deteriorate limb function, and develop hypercalcemia. Treatment of patients should be comprehensive and base on the rational use of systemic therapy and local impacts. The use of bisphosphonates inhibits bone resorption and progression of bone metastases, reduces the risk of complications due to metastatic bone disease including pain. Bisphosphonates significantly reduce the incidence of SRE in patients with bone metastases, diminish the need for analgesic radiotherapy, postpone terms of SRE occurrence, reduce pain syndrome as well as the need for analgetics. They also easily tolerated by patients.
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Base de dados:
MEDLINE
Assunto principal:
Dor
/
Neoplasias Ósseas
/
Difosfonatos
/
Conservadores da Densidade Óssea
/
Manejo da Dor
Limite:
Humans
Idioma:
Ru
Ano de publicação:
2015
Tipo de documento:
Article