No evidence for substrate accumulation in Parkinson brains with GBA mutations.

Gegg, Matthew E; Sweet, Lindsay; Wang, Bing H; Shihabuddin, Lamya S; Sardi, Sergio Pablo; Schapira, Anthony H V

Gegg, Matthew E; Sweet, Lindsay; Wang, Bing H; Shihabuddin, Lamya S; Sardi, Sergio Pablo; Schapira, Anthony H V.

Afiliação

Gegg ME; Department of Clinical Neuroscience, UCL Institute of Neurology, London, UK.
Sweet L; Genzyme, a Sanofi Company, Framingham, Massachusetts, USA.
Wang BH; Genzyme, a Sanofi Company, Framingham, Massachusetts, USA.
Shihabuddin LS; Genzyme, a Sanofi Company, Framingham, Massachusetts, USA.
Sardi SP; Genzyme, a Sanofi Company, Framingham, Massachusetts, USA.
Schapira AH; Department of Clinical Neuroscience, UCL Institute of Neurology, London, UK.

Mov Disord ; 30(8): 1085-9, 2015 Jul.

Article em En | MEDLINE | ID: mdl-26096906

Assuntos

Cerebelo/metabolismo; Glucosilceramidase/metabolismo; Putamen/metabolismo; Bancos de Tecidos; beta-Glucosidase/genética; Cerebelo/patologia; Humanos; Mutação; Putamen/patologia

Palavras-chave

Parkinson's disease; glucocerebrosidase; lysosomes; sphingolipids

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Putamen / Bancos de Tecidos / Cerebelo / Beta-Glucosidase / Glucosilceramidase Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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