New geranylated flavanones from the fruits of Paulownia catalpifolia Gong Tong with their anti-proliferative activity on lung cancer cells A549.

Gao, Tian-yang; Jin, Xing; Tang, Wen-zhao; Wang, Xiao-jing; Zhao, Yun-xue

Gao, Tian-yang; Jin, Xing; Tang, Wen-zhao; Wang, Xiao-jing; Zhao, Yun-xue.

Afiliação

Gao TY; Key Laboratory for Rare Disease of Shandong Province, Institute of Materia Medica, Shandong Academy of Medical Science, Jinan 260062, PR China; School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medicine Sciences, Jinan 250022, PR China; State Key Laboratory of Bioactive S
Jin X; Department of Pharmacology, School of Medicine, Shandong University, Jinan 250012, PR China.
Tang WZ; Key Laboratory for Rare Disease of Shandong Province, Institute of Materia Medica, Shandong Academy of Medical Science, Jinan 260062, PR China; School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medicine Sciences, Jinan 250022, PR China; State Key Laboratory of Bioactive S
Wang XJ; Key Laboratory for Rare Disease of Shandong Province, Institute of Materia Medica, Shandong Academy of Medical Science, Jinan 260062, PR China; School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medicine Sciences, Jinan 250022, PR China. Electronic address: xiaojing6@gmail
Zhao YX; Department of Pharmacology, School of Medicine, Shandong University, Jinan 250012, PR China.

Bioorg Med Chem Lett ; 25(17): 3686-9, 2015 Sep 01.

Article em En | MEDLINE | ID: mdl-26115572

Assuntos

Antineoplásicos Fitogênicos/química; Antineoplásicos Fitogênicos/farmacologia; Neoplasias Pulmonares/tratamento farmacológico; Scrophulariaceae/química; Antineoplásicos Fitogênicos/isolamento & purificação; Linhagem Celular Tumoral/efeitos dos fármacos; Ensaios de Seleção de Medicamentos Antitumorais/métodos; Flavanonas/química; Flavanonas/isolamento & purificação; Flavanonas/farmacologia; Frutas/química; Fase G1/efeitos dos fármacos; Humanos; Neoplasias Pulmonares/patologia; Espectroscopia de Ressonância Magnética; Estrutura Molecular

Palavras-chave

Antiproliferative activity; Geranylated flavanones; Lung cancer cells A549; Paulownia catalpifolia Gong Tong

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Scrophulariaceae / Neoplasias Pulmonares / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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