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Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection.
Pascal, Kristen E; Coleman, Christopher M; Mujica, Alejandro O; Kamat, Vishal; Badithe, Ashok; Fairhurst, Jeanette; Hunt, Charleen; Strein, John; Berrebi, Alexander; Sisk, Jeanne M; Matthews, Krystal L; Babb, Robert; Chen, Gang; Lai, Ka-Man V; Huang, Tammy T; Olson, William; Yancopoulos, George D; Stahl, Neil; Frieman, Matthew B; Kyratsous, Christos A.
Afiliação
  • Pascal KE; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Coleman CM; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201;
  • Mujica AO; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Kamat V; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Badithe A; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Fairhurst J; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Hunt C; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Strein J; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Berrebi A; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201.
  • Sisk JM; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201;
  • Matthews KL; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201;
  • Babb R; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Chen G; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Lai KM; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Huang TT; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Olson W; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Yancopoulos GD; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591; george@regeneron.com christos.kyratsous@regeneron.com.
  • Stahl N; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;
  • Frieman MB; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201;
  • Kyratsous CA; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591; george@regeneron.com christos.kyratsous@regeneron.com.
Proc Natl Acad Sci U S A ; 112(28): 8738-43, 2015 Jul 14.
Article em En | MEDLINE | ID: mdl-26124093
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Coronavirus / Anticorpos Neutralizantes / Glicoproteína da Espícula de Coronavírus / Coronavírus da Síndrome Respiratória do Oriente Médio / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Coronavirus / Anticorpos Neutralizantes / Glicoproteína da Espícula de Coronavírus / Coronavírus da Síndrome Respiratória do Oriente Médio / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article