AGS3 is involved in TNF-&#945; medicated osteogenic differentiation of human dental pulp stem cells.

Xing, Jing; Lian, Min; Shen, Qijie; Feng, Guijuan; Huang, Dan; Lu, Xiaohui; Gu, Zhifeng; Li, Liren; Zhang, Jinglong; Huang, Shen; You, Qingsheng; Wu, Xiang; Zhang, Dongmei; Feng, Xingmei

AGS3 is involved in TNF-α medicated osteogenic differentiation of human dental pulp stem cells.

Xing, Jing; Lian, Min; Shen, Qijie; Feng, Guijuan; Huang, Dan; Lu, Xiaohui; Gu, Zhifeng; Li, Liren; Zhang, Jinglong; Huang, Shen; You, Qingsheng; Wu, Xiang; Zhang, Dongmei; Feng, Xingmei.

Afiliação

Xing J; Department of Stomatology, Affiliated Hospital of Nantong University, Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, China.
Lian M; Department of Stomatology, Affiliated Hospital of Nantong University, Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, China.
Shen Q; Department of Stomatology, Affiliated Hospital of Nantong University, Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, China.
Feng G; Department of Stomatology, Affiliated Hospital of Nantong University, Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, China.
Huang D; Department of Stomatology, Affiliated Hospital of Nantong University, Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, China.
Lu X; Department of Stomatology, Affiliated Hospital of Nantong University, Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, China.
Gu Z; Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong, China.
Li L; Department of Hematology, Affiliated Hospital of Nantong University, Nantong, China.
Zhang J; Department of Spine Surgery, the Second Affiliated Hospital of Nantong University, Nantong, China.
Huang S; Department of Spine Surgery, the Second Affiliated Hospital of Nantong University, Nantong, China.
You Q; Department of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Wu X; Department of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Zhang D; Department of Pathogen Biology, Medical College, Nantong University, Nantong, China. Electronic address: zdm060808@aliyun.com.
Feng X; Department of Stomatology, Affiliated Hospital of Nantong University, Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, China. Electronic address: fengxingmei1220@163.com.

Differentiation ; 89(5): 128-36, 2015 Jun.

Article em En | MEDLINE | ID: mdl-26143356

Assuntos

Polpa Dentária/citologia; Inibidores de Dissociação do Nucleotídeo Guanina/fisiologia; Células-Tronco Multipotentes/citologia; Osteogênese/fisiologia; Fator de Necrose Tumoral alfa; Adulto; Idoso; Proteínas Morfogenéticas Ósseas/genética; Proteínas Morfogenéticas Ósseas/metabolismo; Regulação da Expressão Gênica; Humanos; Proteína 2 Inibidora de Diferenciação/genética; Proteína 2 Inibidora de Diferenciação/metabolismo; Sialoproteína de Ligação à Integrina/genética; Sialoproteína de Ligação à Integrina/metabolismo; Masculino; Pessoa de Meia-Idade; Osteocalcina/genética; Osteocalcina/metabolismo; Osteogênese/efeitos dos fármacos; Transdução de Sinais/efeitos dos fármacos; Fator de Necrose Tumoral alfa/metabolismo; Fator de Necrose Tumoral alfa/farmacologia

Palavras-chave

Activator of G-protein signaling 3 (AGS3); CAMP response element (CRE)-binding protein (CREB); Cyclic 3', 5'-adenosine monophosphate (cAMP); Dental pulp stem cells (DPSCs); Osteogenic differentiation; Protein kinase A (PKA); Tumor necrosis factor α (TNF-α)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteogênese / Fator de Necrose Tumoral alfa / Inibidores de Dissociação do Nucleotídeo Guanina / Células-Tronco Multipotentes / Polpa Dentária Limite: Adult / Aged / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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