Utilizing induced pluripotent stem cells (iPSCs) to understand the actions of estrogens in human neurons.

Shum, Carole; Macedo, Sara C; Warre-Cornish, Katherine; Cocks, Graham; Price, Jack; Srivastava, Deepak P

Shum, Carole; Macedo, Sara C; Warre-Cornish, Katherine; Cocks, Graham; Price, Jack; Srivastava, Deepak P.

Afiliação

Shum C; Department of Basic and Clinical Neuroscience, Cell and Behaviour Unit, The James Black Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK.
Macedo SC; Department of Basic and Clinical Neuroscience, Cell and Behaviour Unit, The James Black Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK; Faculty of Engineering, Universidade do Porto, 4200-465 Porto, Portugal.
Warre-Cornish K; Department of Basic and Clinical Neuroscience, Cell and Behaviour Unit, The James Black Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK.
Cocks G; Department of Basic and Clinical Neuroscience, Cell and Behaviour Unit, The James Black Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK.
Price J; Department of Basic and Clinical Neuroscience, Cell and Behaviour Unit, The James Black Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK.
Srivastava DP; Department of Basic and Clinical Neuroscience, Cell and Behaviour Unit, The James Black Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK. Electronic address: deepak.srivastava@kcl.ac.uk.

Horm Behav ; 74: 228-42, 2015 Aug.

Article em En | MEDLINE | ID: mdl-26143621

Assuntos

Estrogênios/farmacologia; Células-Tronco Pluripotentes Induzidas/efeitos dos fármacos; Neurônios/efeitos dos fármacos; Animais; Diferenciação Celular/efeitos dos fármacos; Humanos; Células-Tronco Pluripotentes Induzidas/fisiologia; Modelos Biológicos; Neurogênese/efeitos dos fármacos; Neurogênese/fisiologia; Neurônios/fisiologia

Palavras-chave

17ß-estradiol; Autism spectrum disorders; Dendrite; Dendritic spines; Estrogen receptor; Neurodegenerative disease; Neurodevelopmental disorders; Psychiatric; Schizophrenia; Stem cells; Synapse

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estrogênios / Células-Tronco Pluripotentes Induzidas / Neurônios Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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