Development of Radiolabeled Membrane Type-1 Matrix Metalloproteinase Activatable Cell Penetrating Peptide Imaging Probes.

van Duijnhoven, Sander M J; Robillard, Marc S; Nicolay, Klaas; Grüll, Holger

van Duijnhoven, Sander M J; Robillard, Marc S; Nicolay, Klaas; Grüll, Holger.

Afiliação

van Duijnhoven SM; Department of Biomedical Engineering, Eindhoven University of Technology, High Tech Campus 11, Eindhoven 5656 AE, The Netherlands. sander_van_duijnhoven@outlook.com.
Robillard MS; Department of Oncology Solutions, Philips Research, High Tech Campus 11, Eindhoven 5656 AE, The Netherlands. sander_van_duijnhoven@outlook.com.
Nicolay K; Tagworks Pharmaceuticals, High Tech Campus 11, Eindhoven 5656 AE, The Netherlands. marc.robillard@tagworkspharma.com.
Grüll H; Department of Biomedical Engineering, Eindhoven University of Technology, High Tech Campus 11, Eindhoven 5656 AE, The Netherlands. k.nicolay@tue.nl.

Molecules ; 20(7): 12076-92, 2015 Jul 02.

Article em En | MEDLINE | ID: mdl-26147581

Assuntos

Peptídeos Penetradores de Células/metabolismo; Metaloproteinase 14 da Matriz/metabolismo; Sondas Moleculares; Radioisótopos/metabolismo; Animais; Linhagem Celular Tumoral; Peptídeos Penetradores de Células/farmacocinética; Humanos; Técnicas In Vitro; Masculino; Camundongos; Especificidade por Substrato; Distribuição Tecidual

Palavras-chave

activatable cell penetrating peptide; matrix metalloproteinase-14; membrane type-1 matrix metalloproteinase; molecular imaging; myocardial infarction; peptide chemistry; radiolabeling

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Radioisótopos / Sondas Moleculares / Metaloproteinase 14 da Matriz / Peptídeos Penetradores de Células Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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