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A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.
Arcaroli, John J; Tai, W M; McWilliams, Ryan; Bagby, Stacey; Blatchford, Patrick J; Varella-Garcia, Marileila; Purkey, Alicia; Quackenbush, Kevin S; Song, Eun-Kee; Pitts, Todd M; Gao, Dexiang; Lieu, Chris; McManus, Martine; Tan, Aik Choon; Zheng, Xianxian; Zhang, Qin; Ozeck, Mark; Olson, Peter; Jiang, Zhi-Qin; Kopetz, Scott; Jimeno, Antonio; Keysar, Stephen; Eckhardt, Gail; Messersmith, Wells A.
Afiliação
  • Arcaroli JJ; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Tai WM; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • McWilliams R; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Bagby S; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Blatchford PJ; Department of Biostatistics & Informatics, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Varella-Garcia M; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Purkey A; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Quackenbush KS; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Song EK; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Pitts TM; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Gao D; Department of Biostatistics & Informatics, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Lieu C; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • McManus M; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Tan AC; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Zheng X; Pfizer Oncology Research Unit, Translational Research, Pfizer, La Jolla, CA.
  • Zhang Q; Pfizer Oncology Research Unit, Translational Research, Pfizer, La Jolla, CA.
  • Ozeck M; Pfizer Oncology Research Unit, Translational Research, Pfizer, La Jolla, CA.
  • Olson P; Pfizer Oncology Research Unit, Translational Research, Pfizer, La Jolla, CA.
  • Jiang ZQ; MD Anderson Cancer Center, Texas Medical Center, Houston, TX.
  • Kopetz S; MD Anderson Cancer Center, Texas Medical Center, Houston, TX.
  • Jimeno A; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Keysar S; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Eckhardt G; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
  • Messersmith WA; Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus and University of Colorado Cancer Center, Aurora, CO.
Int J Cancer ; 138(1): 195-205, 2016 Jan 01.
Article em En | MEDLINE | ID: mdl-26152787
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Dosagem de Genes / Receptor Notch1 / Variações do Número de Cópias de DNA Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Dosagem de Genes / Receptor Notch1 / Variações do Número de Cópias de DNA Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article