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NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity.
Ochodnicka-Mackovicova, Katarina; Bahjat, Mahnoush; Bloedjes, Timon A; Maas, Chiel; de Bruin, Alexander M; Bende, Richard J; van Noesel, Carel J M; Guikema, Jeroen E J.
Afiliação
  • Ochodnicka-Mackovicova K; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and Lymphoma and Myeloma Center Amsterdam, Amsterdam, The Netherlands.
  • Bahjat M; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and Lymphoma and Myeloma Center Amsterdam, Amsterdam, The Netherlands.
  • Bloedjes TA; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and Lymphoma and Myeloma Center Amsterdam, Amsterdam, The Netherlands.
  • Maas C; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and Lymphoma and Myeloma Center Amsterdam, Amsterdam, The Netherlands.
  • de Bruin AM; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and Lymphoma and Myeloma Center Amsterdam, Amsterdam, The Netherlands.
  • Bende RJ; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and Lymphoma and Myeloma Center Amsterdam, Amsterdam, The Netherlands.
  • van Noesel CJ; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and Lymphoma and Myeloma Center Amsterdam, Amsterdam, The Netherlands.
  • Guikema JE; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and Lymphoma and Myeloma Center Amsterdam, Amsterdam, The Netherlands.
Blood ; 126(11): 1324-35, 2015 Sep 10.
Article em En | MEDLINE | ID: mdl-26153519

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / NF-kappa B / Proteínas Proto-Oncogênicas c-akt / Células Precursoras de Linfócitos B Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / NF-kappa B / Proteínas Proto-Oncogênicas c-akt / Células Precursoras de Linfócitos B Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article