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Establishing the UK DNA Bank for motor neuron disease (MND).
Smith, Lucy; Cupid, B C; Dickie, B G M; Al-Chalabi, A; Morrison, K E; Shaw, C E; Shaw, P J.
Afiliação
  • Smith L; Motor Neurone Disease Association, PO Box 246, Northampton, NN1 2PR, UK. lucy.smith@mndassociation.org.
  • Cupid BC; Motor Neurone Disease Association, PO Box 246, Northampton, NN1 2PR, UK. belinda.cupid@mndassociation.org.
  • Dickie BG; Motor Neurone Disease Association, PO Box 246, Northampton, NN1 2PR, UK. brian.dickie@mndassociation.org.
  • Al-Chalabi A; NIHR Biomedical Research Unit in Dementia, Department of Clinical Neuroscience, King's College London, London, SE5 8AF, UK. ammar.al-chalabi@kcl.ac.uk.
  • Morrison KE; Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK. k.morrison@bham.ac.uk.
  • Shaw CE; NIHR Biomedical Research Unit in Dementia, Department of Clinical Neuroscience, King's College London, London, SE5 8AF, UK. chris.shaw@kcl.ac.uk.
  • Shaw PJ; Sheffield Institute for Translational Neuroscience, University of Sheffield, 385A Glossop Road, Sheffield, S10 2HQ, UK. pamela.shaw@sheffield.ac.uk.
BMC Genet ; 16: 84, 2015 Jul 14.
Article em En | MEDLINE | ID: mdl-26170009
ABSTRACT
In 2003 the Motor Neurone Disease (MND) Association, together with The Wellcome Trust, funded the creation of a national DNA Bank specific for MND. It was anticipated that the DNA Bank would constitute an important resource to researchers worldwide and significantly increase activity in MND genetic research. The DNA Bank houses over 3000 high quality DNA samples, all of which were donated by people living with MND, family members and non-related controls, accompanied by clinical phenotype data about the patients. Today the primary focus of the UK MND DNA Bank still remains to identify causative and disease modifying factors for this devastating disease.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Doença dos Neurônios Motores / Bancos de Espécimes Biológicos Tipo de estudo: Prognostic_studies Limite: Humans País como assunto: Europa Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Doença dos Neurônios Motores / Bancos de Espécimes Biológicos Tipo de estudo: Prognostic_studies Limite: Humans País como assunto: Europa Idioma: En Ano de publicação: 2015 Tipo de documento: Article