Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube cancer.

van der Noll, Ruud; Marchetti, Serena; Steeghs, Neeltje; Beijnen, Jos H; Mergui-Roelvink, Marja W J; Harms, Emmy; Rehorst, Harriet; Sonke, Gabe S; Schellens, Jan H M

van der Noll, Ruud; Marchetti, Serena; Steeghs, Neeltje; Beijnen, Jos H; Mergui-Roelvink, Marja W J; Harms, Emmy; Rehorst, Harriet; Sonke, Gabe S; Schellens, Jan H M.

Afiliação

van der Noll R; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.
Marchetti S; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.
Steeghs N; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.
Beijnen JH; 1] Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands [2] Utrecht Institute of Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, Utrecht 3584 CG, The Netherlands.
Mergui-Roelvink MW; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.
Harms E; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.
Rehorst H; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.
Sonke GS; Department of Medical Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.
Schellens JH; 1] Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands [2] Utrecht Institute of Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, Utrecht 3584 CG, The Netherlands.

Br J Cancer ; 113(3): 396-402, 2015 Jul 28.

Article em En | MEDLINE | ID: mdl-26180927

Assuntos

Neoplasias da Mama/tratamento farmacológico; Neoplasias das Tubas Uterinas/tratamento farmacológico; Neoplasias Ovarianas/tratamento farmacológico; Ftalazinas/uso terapêutico; Piperazinas/uso terapêutico; Adulto; Idoso; Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico; Neoplasias da Mama/genética; Neoplasias da Mama/patologia; Carboplatina/administração & dosagem; Progressão da Doença; Neoplasias das Tubas Uterinas/genética; Neoplasias das Tubas Uterinas/patologia; Feminino; Humanos; Pessoa de Meia-Idade; Neoplasias Ovarianas/genética; Neoplasias Ovarianas/patologia; Paclitaxel/administração & dosagem; Terapia de Salvação; Falha de Tratamento

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Ftalazinas / Piperazinas / Neoplasias da Mama / Neoplasias das Tubas Uterinas Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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