Kocher-Debré-Semelaigne syndrome with rhabdomyolysis and increased creatinine.
J Pediatr Endocrinol Metab
; 28(11-12): 1383-5, 2015 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-26181046
ABSTRACT
Association of Kocher-Debré-Semelaigne syndrome-a myopathy of hypothyroidism in childhood characterized by muscular hypertrophy, with rhabdomyolysis is very rare. We present a case of Kocher-Debré-Semelaigne syndrome with rhabdomyolysis secondary to Hashimoto's thyroiditis. He had muscular symptoms simulating poly/dermatomyositis, massively elevated creatine kinase (CK) levels and high creatinine levels. All of the findings reversed on treatment of hypothyroidism. The response to the therapy strongly suggested that Kocher-Debré-Semelaigne (KDS) syndrome was the underlying etiology. Serum thyroid- stimulating hormone levels should be routinely determined in all patients with muscular symptoms and/or elevation of CK and creatinine, keeping KDS syndrome in mind.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Rabdomiólise
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Músculo Esquelético
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Creatinina
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Hipotireoidismo Congênito
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Doença de Hashimoto
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Hipertrofia
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Doenças Musculares
Limite:
Adolescent
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Humans
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Male
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article