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A small molecular agent YL529 inhibits VEGF-D-induced lymphangiogenesis and metastasis in preclinical tumor models in addition to its known antitumor activities.
Xu, Youzhi; Lu, Wenjie; Yang, Peng; Peng, Wen; Wang, Chunting; Li, Manli; Li, Yan; Li, Guobo; Meng, Nana; Lin, Hongjun; Kan, Lixin; Wang, Siying; Yang, Shengyong; Yu, Luoting; Zhao, YingLan.
Afiliação
  • Xu Y; Department of Pathophysiology, School of Basic Medicine, Anhui Medical University, 81#, Mei Shan Road, Hefei, 230032, China. youzhixu08@gmail.com.
  • Lu W; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. youzhixu08@gmail.com.
  • Yang P; Department of Pathophysiology, School of Basic Medicine, Anhui Medical University, 81#, Mei Shan Road, Hefei, 230032, China. eva63136@163.com.
  • Peng W; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. eva63136@163.com.
  • Wang C; Department of Transfusion, the First Affiliated Hospital of Anhui Medical University, 81#, Mei Shan Road, Hefei, 230032, China. 158562771@qq.com.
  • Li M; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. 251241462@qq.com.
  • Li Y; Department of Oncology, The People's Hospital of Guizhou Province, 83#, Zhong Shan East Road, Guiyang, 550004, China. 251241462@qq.com.
  • Li G; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. 553693616@qq.com.
  • Meng N; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. 273107786@qq.com.
  • Lin H; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. 395067922@qq.com.
  • Kan L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. 645328757@qq.com.
  • Wang S; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. 1134079675@qq.com.
  • Yang S; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. dazhisklb@foxmail.com.
  • Yu L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. 1443716876@qq.com.
  • Zhao Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, and Collaborative Innovation Center for Biotherapy, Sichuan University, 17#, 3rd Section, Ren min South Road, Chengdu, 610041, China. 245428988@qq.com.
BMC Cancer ; 15: 525, 2015 Jul 18.
Article em En | MEDLINE | ID: mdl-26187637

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Picolinas / Benzenossulfonatos / Inibidores da Angiogênese / Fator D de Crescimento do Endotélio Vascular / Linfangiogênese / Metástase Linfática / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Picolinas / Benzenossulfonatos / Inibidores da Angiogênese / Fator D de Crescimento do Endotélio Vascular / Linfangiogênese / Metástase Linfática / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article