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Spontaneous retrotransposon insertion into TNF 3'UTR causes heart valve disease and chronic polyarthritis.
Lacey, Derek; Hickey, Peter; Arhatari, Benedicta D; O'Reilly, Lorraine A; Rohrbeck, Leona; Kiriazis, Helen; Du, Xiao-Jun; Bouillet, Philippe.
Afiliação
  • Lacey D; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Melbourne, VIC 3052, Australia;
  • Hickey P; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Melbourne, VIC 3052, Australia;
  • Arhatari BD; Australian Research Council Centre of Excellence for Advanced Molecular Imaging, Department of Physics, La Trobe University, VIC 3086, Australia;
  • O'Reilly LA; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Melbourne, VIC 3052, Australia;
  • Rohrbeck L; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Melbourne, VIC 3052, Australia;
  • Kiriazis H; Baker IDI Heart and Diabetes Institute, and Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.
  • Du XJ; Baker IDI Heart and Diabetes Institute, and Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.
  • Bouillet P; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Melbourne, VIC 3052, Australia; bouillet@wehi.edu.au.
Proc Natl Acad Sci U S A ; 112(31): 9698-703, 2015 Aug 04.
Article em En | MEDLINE | ID: mdl-26195802

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite / Mutagênese Insercional / Fator de Necrose Tumoral alfa / Retroelementos / Regiões 3' não Traduzidas / Doenças das Valvas Cardíacas / Mutação Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite / Mutagênese Insercional / Fator de Necrose Tumoral alfa / Retroelementos / Regiões 3' não Traduzidas / Doenças das Valvas Cardíacas / Mutação Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article