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Critical Care for Multiple Organ Failure Secondary to Ebola Virus Disease in the United States.
Sueblinvong, Viranuj; Johnson, Daniel W; Weinstein, Gary L; Connor, Michael J; Crozier, Ian; Liddell, Allison M; Franch, Harold A; Wall, Bruce R; Kalil, Andre C; Feldman, Mark; Lisco, Steven J; Sevransky, Jonathan E.
Afiliação
  • Sueblinvong V; 1Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA. 2Division of Critical Care, Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE. 3Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Texas Health Presbyterian Hospital, Dallas, TX. 4Division of Renal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA. 5Infectious Dise
Crit Care Med ; 43(10): 2066-75, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26196353
ABSTRACT

OBJECTIVE:

This report describes three patients with Ebola virus disease who were treated in the United States and developed for severe critical illness and multiple organ failure secondary to Ebola virus infection. The patients received mechanical ventilation, renal replacement therapy, invasive monitoring, vasopressor support, and investigational therapies for Ebola virus disease. DATA SOURCES Patient medical records from three tertiary care centers (Emory University Hospital, University of Nebraska Medical Center, and Texas Health Presbyterian Dallas Hospital). STUDY SELECTION Not applicable. DATA EXTRACTION Not applicable. DATA

SYNTHESIS:

Not applicable.

CONCLUSION:

In the severe form, patients with Ebola virus disease may require life-sustaining therapy, including mechanical ventilation and renal replacement therapy. In conjunction with other reported cases, this series suggests that respiratory and renal failure may occur in severe Ebola virus disease, especially in patients burdened with high viral loads. Ebola virus disease complicated by multiple organ failure can be survivable with the application of advanced life support measures. This collective, multicenter experience is presented with the hope that it may inform future treatment of patients with Ebola virus disease requiring critical care treatment.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença pelo Vírus Ebola / Cuidados Críticos / Insuficiência de Múltiplos Órgãos Tipo de estudo: Clinical_trials Limite: Adult / Humans / Male País como assunto: America do norte Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença pelo Vírus Ebola / Cuidados Críticos / Insuficiência de Múltiplos Órgãos Tipo de estudo: Clinical_trials Limite: Adult / Humans / Male País como assunto: America do norte Idioma: En Ano de publicação: 2015 Tipo de documento: Article