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Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro.
Reznícková, Eva; Weitensteiner, Sabine; Havlícek, Libor; Jorda, Radek; Gucký, Tomás; Berka, Karel; Bazgier, Václav; Zahler, Stefan; Krystof, Vladimír; Strnad, Miroslav.
Afiliação
  • Reznícková E; Laboratory of Growth Regulators & Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University and Institute of Experimental Botany AS CR, Slechtitelu 27, 78371, Olomouc, Czech Republic.
  • Weitensteiner S; Department of Pharmacy, LMU Munich - Center for Drug Research - Pharmaceutical Biology, Butenandtstr. 5-13, 81377, Munich, Germany.
  • Havlícek L; Isotope Laboratory, Institute of Experimental Botany ASCR, Vídenská 1083, 14220, Prague, Czech Republic.
  • Jorda R; Laboratory of Growth Regulators & Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University and Institute of Experimental Botany AS CR, Slechtitelu 27, 78371, Olomouc, Czech Republic.
  • Gucký T; Laboratory of Growth Regulators & Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University and Institute of Experimental Botany AS CR, Slechtitelu 27, 78371, Olomouc, Czech Republic.
  • Berka K; Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University, 17. listopadu 12, 77146, Olomouc, Czech Republic.
  • Bazgier V; Laboratory of Growth Regulators & Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University and Institute of Experimental Botany AS CR, Slechtitelu 27, 78371, Olomouc, Czech Republic.
  • Zahler S; Department of Physical Chemistry, Faculty of Science, Palacký University, 17. listopadu 1192/12, 771 46, Olomouc, Czech Republic.
  • Krystof V; Department of Pharmacy, LMU Munich - Center for Drug Research - Pharmaceutical Biology, Butenandtstr. 5-13, 81377, Munich, Germany.
  • Strnad M; Laboratory of Growth Regulators & Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Palacký University and Institute of Experimental Botany AS CR, Slechtitelu 27, 78371, Olomouc, Czech Republic.
Chem Biol Drug Des ; 86(6): 1528-40, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26198005

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Quinase 5 Dependente de Ciclina / Quinase 2 Dependente de Ciclina / Aurora Quinase A Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Quinase 5 Dependente de Ciclina / Quinase 2 Dependente de Ciclina / Aurora Quinase A Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article