Phosphonate monoesters on a thiacalix[4]arene framework as potential inhibitors of protein tyrosine phosphatase 1B.
Org Biomol Chem
; 13(33): 8803-6, 2015 Sep 07.
Article
em En
| MEDLINE
| ID: mdl-26205135
ABSTRACT
Monoester derivatives of thiacalix[4]arene tetrakis(methylphosphonic) acid were found to be capable of inhibiting protein tyrosine phosphatase 1B. In addition, these compounds can strongly bind to human serum albumin.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Calixarenos
/
Inibidores Enzimáticos
/
Ésteres
/
Proteína Tirosina Fosfatase não Receptora Tipo 1
/
Organofosfonatos
Limite:
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article