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Isolated ocular lichen planus in a child.
Igras, Estera; Kennedy, Susan; MacDermott, Emma Jane; Murphy, Conor C.
Afiliação
  • Igras E; Department of Ophthalmology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland. Electronic address: estera_igras@hotmail.com.
  • Kennedy S; Department of Ophthalmic Pathology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland.
  • MacDermott EJ; National Centre for Paediatric Rheumatology, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland.
  • Murphy CC; Department of Ophthalmology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland; Department of Ophthalmology, Royal College of Surgeons in Ireland, Dublin, Ireland.
J AAPOS ; 19(4): 381-3, 2015 Aug.
Article em En | MEDLINE | ID: mdl-26212185
Lichen planus (LP) is an autoimmune inflammatory condition of the skin and mucous membranes, of unknown aetiology, that infrequently involves the eye. Ocular LP has not been described in children. We present the case of an 8-year-old girl with severe, filamentous dry eyes and persistent conjunctival hyperemia with bilateral progressive conjunctival symblepharon. Her conjunctival biopsy showed heavy linear fibrinogen deposits along the basement membrane without IgG, IgA, IgM, or C3 deposition, consistent with LP. No skin or other mucosal lesions were present, suggesting a diagnosis of isolated conjunctival LP. Oral and topical cyclosporine combined with methotrexate and low-dose oral steroids led to sustained disease remission. To our knowledge, this is the first case of isolated ocular LP in a child.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Doenças da Túnica Conjuntiva / Líquen Plano Tipo de estudo: Diagnostic_studies Limite: Child / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Doenças da Túnica Conjuntiva / Líquen Plano Tipo de estudo: Diagnostic_studies Limite: Child / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article