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Click modification of diazido acridine intercalators: a versatile route towards decorated DNA nanostructures.
Moradpour Hafshejani, Shahrbanou; Watson, Scott M D; Tuite, Eimer M; Pike, Andrew R.
Afiliação
  • Moradpour Hafshejani S; School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU (UK).
  • Watson SM; School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU (UK).
  • Tuite EM; School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU (UK). eimer.tuite@ncl.ac.uk.
  • Pike AR; School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU (UK). andrew.pike@ncl.ac.uk.
Chemistry ; 21(36): 12611-5, 2015 Sep 01.
Article em En | MEDLINE | ID: mdl-26216718
ABSTRACT
Diazido derivatives of 3,6-diamino acridine (proflavine) intercalate into DNA and undergo functionalization through click chemistry to form 1D nanostructures with redox active, conductive nanowire, and fluorescent properties. This two-step approach, intercalation followed by click modification allows for the controlled decoration of DNA nanostructures.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acridinas / DNA / Nanoestruturas / Substâncias Intercalantes Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acridinas / DNA / Nanoestruturas / Substâncias Intercalantes Idioma: En Ano de publicação: 2015 Tipo de documento: Article