Subject satisfaction with onabotulinumtoxinA treatment of glabellar and lateral canthal lines using a new patient-reported outcome measure.
Dermatol Surg
; 41(8): 950-9, 2015 Aug.
Article
em En
| MEDLINE
| ID: mdl-26218728
ABSTRACT
BACKGROUND:
Patient satisfaction with treatment is an important outcome in facial aesthetic medicine.OBJECTIVE:
To evaluate subject satisfaction with onabotulinumtoxinA treatment of glabellar lines (GL) and crow's feet lines (CFL) using the validated Facial Line Satisfaction Questionnaire (FLSQ).METHODS:
In this randomized double-blind study, subjects with moderate/severe GL and CFL received onabotulinumtoxinA (20 U, GL; 24 U, CFL) or placebo. Over 120 days, the following were assessed satisfaction, achievement of treatment expectations, satisfaction with duration of treatment (FLSQ), severity of GL and CFL (Facial Wrinkle Scale [FWS]), and aesthetic improvement (Global Aesthetic Improvement Scale).RESULTS:
Satisfaction in the per-protocol population was significantly greater at Day 60 in the onabotulinumtoxinA group (n = 60) compared with placebo (n = 57) for GL (81.7% vs 0%; p < .001). Most subjects treated with onabotulinumtoxinA remained satisfied up to 120 days. Achievement of treatment expectations (86.7%; Day 60), satisfaction (81.7%; Day 60), and satisfaction with the duration of treatment (61.6%; Day 90) were significantly better with onabotulinumtoxinA than placebo (p < .001) for GL and CFL combined. Efficacy (FWS) and aesthetic improvement were observed in most subjects at Days 30 and 60, respectively.CONCLUSION:
High satisfaction rates are achieved and sustained in subjects treated with onabotulinumtoxinA for GL and CFL combined.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Envelhecimento da Pele
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Inquéritos e Questionários
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Satisfação do Paciente
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Toxinas Botulínicas Tipo A
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Inibidores da Liberação da Acetilcolina
Tipo de estudo:
Clinical_trials
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Guideline
Limite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article