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Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials.
McConville, Matthew; Fernández, Jorge; Angulo-Barturen, Íñigo; Bahamontes-Rosa, Noemi; Ballell-Pages, Lluis; Castañeda, Pablo; de Cózar, Cristina; Crespo, Benigno; Guijarro, Laura; Jiménez-Díaz, María Belén; Martínez-Martínez, Maria S; de Mercado, Jaime; Santos-Villarejo, Ángel; Sanz, Laura M; Frigerio, Micol; Washbourn, Gina; Ward, Stephen A; Nixon, Gemma L; Biagini, Giancarlo A; Berry, Neil G; Blackman, Michael J; Calderón, Félix; O'Neill, Paul M.
Afiliação
  • McConville M; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Fernández J; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Angulo-Barturen Í; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Bahamontes-Rosa N; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Ballell-Pages L; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Castañeda P; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • de Cózar C; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Crespo B; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Guijarro L; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Jiménez-Díaz MB; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Martínez-Martínez MS; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • de Mercado J; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Santos-Villarejo Á; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Sanz LM; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • Frigerio M; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, United Kingdom.
  • Washbourn G; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, United Kingdom.
  • Ward SA; Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, United Kingdom.
  • Nixon GL; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, United Kingdom.
  • Biagini GA; Liverpool School of Tropical Medicine , Pembroke Place, Liverpool L3 5QA, United Kingdom.
  • Berry NG; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, United Kingdom.
  • Blackman MJ; Division of Parasitology, MRC National Institute for Medical Research , Mill Hill, London NW7 1AA, United Kingdom.
  • Calderón F; Tres Cantos Medicines Development Campus, DDW, GlaxoSmithKline , Severo Ochoa 2, 28760 Tres Cantos, Spain.
  • O'Neill PM; Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, United Kingdom.
J Med Chem ; 58(16): 6448-55, 2015 Aug 27.
Article em En | MEDLINE | ID: mdl-26222445
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis / Inibidores de Serina Proteinase / Antimaláricos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis / Inibidores de Serina Proteinase / Antimaláricos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article