Room-Temperature Decarboxylative Couplings of α-Oxocarboxylates with Aryl Halides by Merging Photoredox with Palladium Catalysis.
Chemistry
; 21(38): 13191-5, 2015 Sep 14.
Article
em En
| MEDLINE
| ID: mdl-26230749
ABSTRACT
Enabled by merging iridium photoredox catalysis and palladium catalysis, α-oxocarboxylate salts can be decarboxylatively coupled with aryl halides to generate aromatic ketones and amides at room temperature. DFT calculations suggest that this reaction proceeds through a Pd(0) -Pd(II) -Pd(III) pathway, in which the Pd(III) intermediate is responsible for reoxidizing Ir(II) to complete the Ir(III) -*Ir(III) -Ir(II) photoredox cycle.
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MEDLINE
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En
Ano de publicação:
2015
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Article