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Identification of a Dual Inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) Pathways.
Byun, Sanguine; Lim, Semi; Mun, Ji Young; Kim, Ki Hyun; Ramadhar, Timothy R; Farrand, Lee; Shin, Seung Ho; Thimmegowda, N R; Lee, Hyong Joo; Frank, David A; Clardy, Jon; Lee, Sam W; Lee, Ki Won.
Afiliação
  • Byun S; From the Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, Advanced Institutes of Convergence Technology, Seoul National University, Suwon 443-270, Republic of Korea.
  • Lim S; WCU Biomodulation Major, Department of Agricultural Biotechnology, Seoul National University, Seoul 151-742, Republic of Korea.
  • Mun JY; Department of Biomedical Laboratory Science, College of Health Sciences, Eulji University, Seongnam 461-463, Republic of Korea.
  • Kim KH; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
  • Ramadhar TR; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115.
  • Farrand L; Yuhan Research Institute, Yuhan Corp., Yongin 446-902, Republic of Korea.
  • Shin SH; Program in Biomedical Informatics and Computational Biology, University of Minnesota, Minneapolis, Minnesota 55455.
  • Thimmegowda NR; Department of Chemistry, Government Sri Krishnarajendra Silver Jubilee Technological Institute, Bangalore 560001, India, World Class Institute, Korea Research Institute of Bioscience and Biotechnology, Ochang 363-883, Korea.
  • Lee HJ; WCU Biomodulation Major, Department of Agricultural Biotechnology, Seoul National University, Seoul 151-742, Republic of Korea.
  • Frank DA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, and.
  • Clardy J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, jon_clardy@hms.harvard.edu.
  • Lee SW; From the Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, swlee@mgh.harvard.edu.
  • Lee KW; Advanced Institutes of Convergence Technology, Seoul National University, Suwon 443-270, Republic of Korea, WCU Biomodulation Major, Department of Agricultural Biotechnology, Seoul National University, Seoul 151-742, Republic of Korea, kiwon@snu.ac.kr.
J Biol Chem ; 290(39): 23553-62, 2015 Sep 25.
Article em En | MEDLINE | ID: mdl-26242912
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apoptose / Diarileptanoides / Proteínas Quinases S6 Ribossômicas 70-kDa / Inibidores Enzimáticos / Janus Quinase 2 Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apoptose / Diarileptanoides / Proteínas Quinases S6 Ribossômicas 70-kDa / Inibidores Enzimáticos / Janus Quinase 2 Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article