Primary cutaneous follicular helper T-cell lymphoma.
J Cutan Pathol
; 43(2): 164-70, 2016 Feb.
Article
em En
| MEDLINE
| ID: mdl-26282465
ABSTRACT
Follicular helper T-cells (TFH) represent a specific subset of CD4-positive helper T-cells that help B-cells to differentiate into long-lived antibody-secreting plasma cells or memory B-cells. The expression of TFH markers in neoplastic T-cells, traditionally related to the angioimmunoblastic (AITL) subgroup of peripheral T-cell lymphomas, is nowadays well-known to be more widespread than previously thought. We report hereby a case of cutaneous T-cell lymphoma in a 75-year-old woman, whose morphological and immunophenotypical features raises the differential diagnosis between cutaneous involvement by AITL and the recently described primary cutaneous T-cell lymphoma with follicular helper-phenotype.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
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Linfoma Cutâneo de Células T
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Linfoma de Células T Periférico
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Linfoma Folicular
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Linfócitos T Reguladores
Limite:
Aged
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Female
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Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article