Digging Deep for New Compounds from the Compass Plant, Silphium laciniatum.
J Nat Prod
; 78(8): 2074-86, 2015 Aug 28.
Article
em En
| MEDLINE
| ID: mdl-26287548
ABSTRACT
The compass plant, Silphium laciniatum, is an iconic perennial plant of the North American tallgrass prairie. The plants of the tallgrass prairie historically have been subjected to a number of biological and environmental stresses. Among the adaptations developed by S. laciniatum is a large deep taproot. An investigation of the secondary metabolites found in the root of a S. laciniatum specimen has led to the identification of 15 new terpenoids (3-8, 10-17, and 22), which were screened for cytotoxic activity in the NCI-H460 human large-cell lung carcinoma cell line.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Terpenos
/
Asteraceae
Tipo de estudo:
Prognostic_studies
Limite:
Humans
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article