[Pagetoid reticulosis (Woringer-Kolopp disease)]. / Pagetoid reticulosis (morbus Woringer-Kolopp).

ABSTRACT

The first Polish report of a case of the limited variety of the Woringer-Kolopp disease (pagetoid reticulosis) is presented. The diagnosis was based on histological examination. Numerous pagetoid cells were found in the epidermis and only few in the dermis. In ultramicroscopy two types of mononuclear cells were disclosed, one with large nucleus and scattered chromatin, and other with smaller nucleus and nuclear chromatin condensed at the periphery. The immunopathological examination of isolated pagetoid cells with monoclonal antibodies showed on their surface a slight prevalence of suppressor T-cell receptors. Radiotherapy was applied with a very good result.