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Morphine preconditioning confers cardioprotection in doxorubicin-induced failing rat hearts via ERK/GSK-3ß pathway independent of PI3K/Akt.
He, Shu-Fang; Jin, Shi-Yun; Wu, Hao; Wang, Bin; Wu, Yun-Xiang; Zhang, Shu-Jie; Irwin, Michael G; Wong, Tak-Ming; Zhang, Ye.
Afiliação
  • He SF; Department of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China.
  • Jin SY; Department of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China.
  • Wu H; Department of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China.
  • Wang B; Department of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China.
  • Wu YX; Department of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China.
  • Zhang SJ; Department of Ultrasound, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China.
  • Irwin MG; Department of Anesthesiology, University of Hong Kong, Hong Kong.
  • Wong TM; Department of Anesthesiology, University of Hong Kong, Hong Kong.
  • Zhang Y; Department of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China. Electronic address: zhangye_hassan@aliyun.com.
Toxicol Appl Pharmacol ; 288(3): 349-58, 2015 Nov 01.
Article em En | MEDLINE | ID: mdl-26296503
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiotônicos / Doxorrubicina / Fosfatidilinositol 3-Quinases / Quinase 3 da Glicogênio Sintase / MAP Quinases Reguladas por Sinal Extracelular / Proteínas Proto-Oncogênicas c-akt / Morfina Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiotônicos / Doxorrubicina / Fosfatidilinositol 3-Quinases / Quinase 3 da Glicogênio Sintase / MAP Quinases Reguladas por Sinal Extracelular / Proteínas Proto-Oncogênicas c-akt / Morfina Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article