Kidney function changes with aging in adults: comparison between cross-sectional and longitudinal data analyses in renal function assessment.

Chung, Sang M; Lee, David J; Hand, Austin; Young, Philip; Vaidyanathan, Jayabharathi; Sahajwalla, Chandrahas

Chung, Sang M; Lee, David J; Hand, Austin; Young, Philip; Vaidyanathan, Jayabharathi; Sahajwalla, Chandrahas.

Afiliação

Chung SM; Office of Clinical Pharmacology (OCP), Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Lee DJ; Office of Clinical Pharmacology (OCP), Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Hand A; Quintiles, Austin, Texas, USA.
Young P; Baylor University, Waco, Texas, USA.
Vaidyanathan J; Office of Clinical Pharmacology (OCP), Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Sahajwalla C; Office of Clinical Pharmacology (OCP), Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.

Biopharm Drug Dispos ; 36(9): 613-21, 2015 Dec.

Article em En | MEDLINE | ID: mdl-26301459

Assuntos

Envelhecimento; Rim/fisiopatologia; Modelos Biológicos; Farmacocinética; Medicina de Precisão/métodos; Insuficiência Renal/fisiopatologia; Adulto; Idoso; Idoso de 80 Anos ou mais; Biomarcadores/sangue; Ensaios Clínicos como Assunto; Creatinina/sangue; Estudos Transversais; Feminino; Taxa de Filtração Glomerular; Humanos; Rim/crescimento & desenvolvimento; Rim/fisiologia; Estudos Longitudinais; Masculino; Pessoa de Meia-Idade; Insuficiência Renal/sangue; Insuficiência Renal/epidemiologia; Risco

Palavras-chave

cross-sectional analysis; longitudinal analysis; renal function decline rates

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Farmacocinética / Insuficiência Renal / Medicina de Precisão / Rim / Modelos Biológicos Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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