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[Effect evaluation of a 2 dose varicella vaccine immunization strategy implemented to control outbreaks in school and kindergarten settings].
Suo, Luodan; Li, Juan; Zhao, Dan; Yang, Fan; Liu, Weixiang; Wu, Jiang; Pang, Xinghuo; Deng, Ying; Lu, Li.
Afiliação
  • Suo L; Institute for Immunization and Prevetion, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
  • Li J; Institute for Immunization and Prevetion, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
  • Zhao D; Institute for Immunization and Prevetion, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
  • Yang F; Institute for Immunization and Prevetion, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
  • Liu W; Institute for Immunization and Prevetion, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
  • Wu J; Institute for Immunization and Prevetion, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
  • Pang X; Institute for Immunization and Prevetion, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
  • Deng Y; Institute for Immunization and Prevetion, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
  • Lu L; Institute for Immunization and Prevetion, Beijing Center for Disease Prevention and Control, Beijing 100013, China; Email: lulibj@sina.com.
Zhonghua Yu Fang Yi Xue Za Zhi ; 49(6): 485-9, 2015 Jun.
Article em Zh | MEDLINE | ID: mdl-26310331
ABSTRACT

OBJECTIVE:

To evaluate the effect of outbreaks control in school settings after a 2 dose varicella vaccine immunization strategy implemented in Beijing.

METHODS:

Epidemiological data of varicella outbreaks in school and kindergarten settings, which were reported by all 16 districts (county) during 2007-2013 according to the technical management norms of Beijing, was collected. The first dose and second dose varicella vaccine coverage rate of eligible children after the 2 dose varicella vaccine immunization strategy implementation were estimated through BJIIMS. Based on above we analyzed the changes of outbreak quantity, case quantity and the distribution characteristics between the pre-adjustment era (2007-2011 years) and late adjustment era (2013) of the 2 dose immunization strategy.

RESULTS:

In pre-adjustment era (2007-2011 years), an average of 74 (95% CI 60-89) outbreaks was reported and 964 (95% CI 812-1 116) cases were involved per year. In late adjustment era (2013) Outbreaks (35) declined 52.7%, involved cases (371) declined 61.5%; Outbreaks epidemic duration shortened from 22 days of pre-adjustment era to 18 days; Outbreaks involved 10-24 cases declined 64.7% (from 34 to 12); Outbreaks involved ≥ 25 cases declined 71.4% (from 7 to 2); Outbreaks of different school type as well as different regions without exception declined dramatically. Cumulative one-dose vaccine coverage in children of 2-6 yr of age was 89.6% (812 859/907 579), and cumulative second-dose vaccine coverage in children of 4-7 yr of age was 44.3% (289 764/647 732).

CONCLUSION:

Implementation of a 2 dose varicella vaccine immunization strategy effectively controlled outbreaks in school and kindergarten settings.
Assuntos
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Base de dados: MEDLINE Assunto principal: Instituições Acadêmicas / Surtos de Doenças / Vacinação / Vacina contra Varicela Limite: Child / Child, preschool / Humans Idioma: Zh Ano de publicação: 2015 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Instituições Acadêmicas / Surtos de Doenças / Vacinação / Vacina contra Varicela Limite: Child / Child, preschool / Humans Idioma: Zh Ano de publicação: 2015 Tipo de documento: Article