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Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition.
Nicholson, Lindsay; Evans, Caroline A; Matheson, Elizabeth; Minto, Lynne; Keilty, Christopher; Sanichar, Maryna; Case, Marian; Schwab, Claire; Williamson, Daniel; Rainer, Johannes; Harrison, Christine J; Kofler, Reinhard; Hall, Andrew G; Redfern, Christopher P F; Whetton, Anthony D; Irving, Julie A E.
Afiliação
  • Nicholson L; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Evans CA; Stem Cell and Leukaemia Proteomics Laboratory, School of Cancer and Enabling Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
  • Matheson E; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Minto L; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Keilty C; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Sanichar M; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Case M; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Schwab C; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Williamson D; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Rainer J; Tyrolean Cancer Research Institute, Innsbruck, Austria.
  • Harrison CJ; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Kofler R; Tyrolean Cancer Research Institute, Innsbruck, Austria.
  • Hall AG; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Redfern CP; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Whetton AD; Stem Cell and Leukaemia Proteomics Laboratory, School of Cancer and Enabling Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
  • Irving JA; Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
Br J Haematol ; 171(4): 595-605, 2015 Nov.
Article em En | MEDLINE | ID: mdl-26310606
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dexametasona / Linfócitos B / Leucemia-Linfoma Linfoblástico de Células Precursoras B / Resistencia a Medicamentos Antineoplásicos / Sistema de Sinalização das MAP Quinases / Proteômica / MAP Quinase Quinase 4 / Inibidores de Proteínas Quinases / Proteínas de Neoplasias / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dexametasona / Linfócitos B / Leucemia-Linfoma Linfoblástico de Células Precursoras B / Resistencia a Medicamentos Antineoplásicos / Sistema de Sinalização das MAP Quinases / Proteômica / MAP Quinase Quinase 4 / Inibidores de Proteínas Quinases / Proteínas de Neoplasias / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article