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Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete congenital stationary night blindness.
Scalabrino, Miranda L; Boye, Sanford L; Fransen, Kathryn M H; Noel, Jennifer M; Dyka, Frank M; Min, Seok Hong; Ruan, Qing; De Leeuw, Charles N; Simpson, Elizabeth M; Gregg, Ronald G; McCall, Maureen A; Peachey, Neal S; Boye, Shannon E.
Afiliação
  • Scalabrino ML; Department of Ophthalmology and.
  • Boye SL; Department of Ophthalmology and.
  • Fransen KM; Department of Ophthalmology and Visual Sciences.
  • Noel JM; Department of Anatomical Sciences and Neurobiology and.
  • Dyka FM; Department of Ophthalmology and.
  • Min SH; Department of Ophthalmology and.
  • Ruan Q; Department of Ophthalmology and.
  • De Leeuw CN; Centre for Molecular Medicine and Therapeutics at the Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada V5Z 4H4, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.
  • Simpson EM; Centre for Molecular Medicine and Therapeutics at the Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada V5Z 4H4, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.
  • Gregg RG; Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, KY 40202, USA.
  • McCall MA; Department of Ophthalmology and Visual Sciences, Department of Anatomical Sciences and Neurobiology and.
  • Peachey NS; Louis Stokes Cleveland VA Medical Center, Cleveland, OH 44106, USA, Cole Eye Institute, Cleveland Clinic, Cleveland, OH 44195, USA and Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA.
  • Boye SE; Department of Ophthalmology and, Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, FL 32610, USA, shannon.boye@eye.ufl.edu.
Hum Mol Genet ; 24(21): 6229-39, 2015 Nov 01.
Article em En | MEDLINE | ID: mdl-26310623
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteoglicanas / Oftalmopatias Hereditárias / Cegueira Noturna / Dependovirus / Doenças Genéticas Ligadas ao Cromossomo X / Células Bipolares da Retina / Vetores Genéticos / Miopia Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteoglicanas / Oftalmopatias Hereditárias / Cegueira Noturna / Dependovirus / Doenças Genéticas Ligadas ao Cromossomo X / Células Bipolares da Retina / Vetores Genéticos / Miopia Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article