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Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.
Chiappinelli, Katherine B; Strissel, Pamela L; Desrichard, Alexis; Li, Huili; Henke, Christine; Akman, Benjamin; Hein, Alexander; Rote, Neal S; Cope, Leslie M; Snyder, Alexandra; Makarov, Vladimir; Budhu, Sadna; Buhu, Sadna; Slamon, Dennis J; Wolchok, Jedd D; Pardoll, Drew M; Beckmann, Matthias W; Zahnow, Cynthia A; Merghoub, Taha; Mergoub, Taha; Chan, Timothy A; Baylin, Stephen B; Strick, Reiner.
Afiliação
  • Chiappinelli KB; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA.
  • Strissel PL; Department of Gynaecology and Obstetrics, Laboratory for Molecular Medicine, University-Clinic Erlangen, 91054 Erlangen, Germany.
  • Desrichard A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Li H; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA.
  • Henke C; Department of Gynaecology and Obstetrics, Laboratory for Molecular Medicine, University-Clinic Erlangen, 91054 Erlangen, Germany.
  • Akman B; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA.
  • Hein A; Department of Gynaecology and Obstetrics, Laboratory for Molecular Medicine, University-Clinic Erlangen, 91054 Erlangen, Germany.
  • Rote NS; Department of Reproductive Biology, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Cope LM; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA.
  • Snyder A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Makarov V; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Buhu S; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Slamon DJ; The Jonsson Comprehensive Cancer Center, University of California-Los Angeles, Los Angeles, CA 90095, USA.
  • Wolchok JD; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Pardoll DM; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA.
  • Beckmann MW; Department of Gynaecology and Obstetrics, Laboratory for Molecular Medicine, University-Clinic Erlangen, 91054 Erlangen, Germany.
  • Zahnow CA; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA.
  • Mergoub T; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Chan TA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Baylin SB; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA. Electronic address: sbaylin@jhmi.edu.
  • Strick R; Department of Gynaecology and Obstetrics, Laboratory for Molecular Medicine, University-Clinic Erlangen, 91054 Erlangen, Germany. Electronic address: reiner.strick@uk-erlangen.de.
Cell ; 162(5): 974-86, 2015 Aug 27.
Article em En | MEDLINE | ID: mdl-26317466
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Interferon Tipo I / Metilação de DNA / Melanoma Tipo de estudo: Etiology_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Interferon Tipo I / Metilação de DNA / Melanoma Tipo de estudo: Etiology_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article