Helical peptaibol mimics are better ionophores when racemic than when enantiopure.
Org Biomol Chem
; 13(37): 9580-4, 2015 Oct 07.
Article
em En
| MEDLINE
| ID: mdl-26327434
Helical peptide foldamers rich in α-aminoisobutyric acid (Aib) act as peptaibol-mimicking ionophores in the phospholipid bilayers of artificial vesicles. Racemic samples of these foldamers are more active than their enantiopure counterparts, which was attributed to differing propensities to form aggregates with crystal-like features in the bilayer.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Peptaibols
/
Peptidomiméticos
/
Ionóforos
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article