Activation of protein kinase C&#945; increases phosphorylation of the UT-A1 urea transporter at serine 494 in the inner medullary collecting duct.

Blount, Mitsi A; Cipriani, Penelope; Redd, Sara K; Ordas, Ronald J; Black, Lauren N; Gumina, Diane L; Hoban, Carol A; Klein, Janet D; Sands, Jeff M

Activation of protein kinase Cα increases phosphorylation of the UT-A1 urea transporter at serine 494 in the inner medullary collecting duct.

Blount, Mitsi A; Cipriani, Penelope; Redd, Sara K; Ordas, Ronald J; Black, Lauren N; Gumina, Diane L; Hoban, Carol A; Klein, Janet D; Sands, Jeff M.

Afiliação

Blount MA; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; and Department of Physiology, Emory University School of Medicine, Atlanta, Georgia mabloun@emory.edu.
Cipriani P; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; and.
Redd SK; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; and.
Ordas RJ; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; and.
Black LN; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; and.
Gumina DL; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; and.
Hoban CA; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; and.
Klein JD; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; and Department of Physiology, Emory University School of Medicine, Atlanta, Georgia.
Sands JM; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; and Department of Physiology, Emory University School of Medicine, Atlanta, Georgia.

Am J Physiol Cell Physiol ; 309(9): C608-15, 2015 Nov 01.

Article em En | MEDLINE | ID: mdl-26333598

Assuntos

Membrana Celular/enzimologia; Medula Renal/enzimologia; Túbulos Renais Coletores/enzimologia; Proteínas de Membrana Transportadoras/metabolismo; Proteína Quinase C-alfa/metabolismo; Animais; Membrana Celular/efeitos dos fármacos; AMP Cíclico/metabolismo; Proteínas Quinases Dependentes de AMP Cíclico/metabolismo; Ativação Enzimática; Ativadores de Enzimas/farmacologia; Soluções Hipertônicas/farmacologia; Medula Renal/efeitos dos fármacos; Túbulos Renais Coletores/efeitos dos fármacos; Células LLC-PK1; Masculino; Proteínas de Membrana Transportadoras/genética; Camundongos; Mutagênese Sítio-Dirigida; Mutação; Osmose; Fosforilação; Proteína Quinase C-alfa/antagonistas & inibidores; Inibidores de Proteínas Quinases/farmacologia; Transporte Proteico; Ratos Sprague-Dawley; Serina; Suínos; Transfecção; Transportadores de Ureia

Palavras-chave

PKC; UT-A1; cAMP; urea transport; vasopressin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Membrana Celular / Proteína Quinase C-alfa / Medula Renal / Túbulos Renais Coletores Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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